Cats are unusually dependent on a constant supply of the amino acid arginine, and a diet lacking arginine causes marked weight loss and can be rapidly fatal.[115] Arginine is an essential additive in cat food because cats have low levels of the enzymes aminotransferase and pyrroline-5-carboxylate which are responsible for the synthesis of ornithine and citrulline in the small intestine. Citrulline would typically go on to the kidneys to make arginine, but because cats have a deficiency in the enzymes that make it, citrulline is not produced in adequate quantities to make arginine. Arginine is essential in the urea cycle in order to convert the toxic component ammonia into urea that can then be excreted in the urine. Because of its essential role, deficiency in arginine results in a buildup of toxic ammonia and leads to hyperammonemia.[116] The symptoms of hyperammonemia include lethargy, vomiting, ataxia, hyperesthesia and can be serious enough to induce death and coma in a matter of days if a cat is being fed an arginine-free diet. The quick onset of these symptoms is due to the fact that diets devoid in arginine will typically still contain all of the other amino acids, which will continue to be catabolized by the body, producing mass amounts of ammonia that very quickly build up with no way of being excreted.[citation needed]
Cats is a sung-through musical composed by Andrew Lloyd Webber, based on the 1939 poetry book Old Possum's Book of Practical Cats by T. S. Eliot. It tells the story of a tribe of cats called the Jellicles and the night they make the "Jellicle choice", deciding which cat will ascend to the Heaviside Layer and come back to a new life. The musical includes the well-known song "Memory" as sung by Grizabella.
Cats is completely told through music with no dialogue in between the songs,[74] although there are occasions when the music accompanies spoken verse. Lloyd Webber's compositions employ an eclectic range of musical styles so as to magnify the characters' contrasting personalities.[4] For example, the rebellious Rum Tum Tugger is introduced with a rock song ("The Rum Tum Tugger"); the fallen Grizabella is accompanied by a dramatic operatic aria ("Grizabella: The Glamour Cat"); Old Deuteronomy makes his grand entrance to a lullaby-turned-anthem ("Old Deuteronomy"); and Gus' nostalgia for the past is reflected through an old-fashioned music hall number ("Gus: The Theatre Cat").[16] Many of the songs are pastiches of their respective genres, which Snelson attributes to the show's origins as a song cycle:
^ Jump up to: a b Cameron-Beaumont, Charlotte; Lowe, Sarah E.; Bradshaw, John W. S. (2002). "Evidence Suggesting Pre-adaptation to Domestication Throughout the Small Felidae" (PDF). Biological Journal of the Linnean Society. 75 (3): 361–366. doi:10.1046/j.1095-8312.2002.00028.x. Archived from the original (PDF) on 9 June 2011. Retrieved 29 September 2009.
The first Australian production ran from July 1985 to August 1987 at the Theatre Royal in Sydney. The original Sydney cast included Debra Byrne as Grizabella, Marina Prior as Jellylorum, Jeff Phillips as Rum Tum Tugger, David Atkins as Mistoffelees, and Anita Louise Combe as Sillabub.[118][230] It then moved to Her Majesty's Theatre in Melbourne where it played from October 1987 to December 1988, with Femi Taylor as Bombalurina and Seán Martin Hingston as Plato/Macavity.[118][231] From 1989 to 1990, the company toured the Festival Theatre in Adelaide,[232] His Majesty's Theatre in Perth,[233] Civic Theatre in Newcastle, Lyric Theatre in Brisbane, and the Aotea Centre in Auckland.[118] This was followed by a second national tour from 1993 to 1996,[234] during which Delia Hannah made her debut as Grizabella in 1994.[235] A professional circus adaptation of Cats, titled Cats Run Away to the Circus, had a national tent tour from 1999 to 2001, with Hannah once again starring as Grizabella.[236][237] Hannah reprised her role for another production that toured Australia and Asia in 2009 and 2010.[238]

There have been numerous notable performers in the Japanese production, including Shintarō Sonooka as Munkustrap (original 1983 cast),[170] Kanji Ishimaru as Skimbleshanks (1992),[171] Masachika Ichimura, and Mayo Kawasaki.[172] Yoshiko Hattori (ja:服部良子) holds the production's record for the longest-appearing cast member; she played Jennyanydots in the original 1983 cast and remained in the role for 20 years with a final performance tally of 4,251.[172]

^ Jump up to: a b Lipinski, Monika J.; Froenicke, Lutz; Baysac, Kathleen C.; Billings, Nicholas C.; Leutenegger, Christian M.; Levy, Alon M.; Longeri, Maria; Niini, Tirri; Ozpinar, Haydar (2008). "The Ascent of Cat Breeds: Genetic Evaluations of Breeds and Worldwide Random-bred Populations". Genomics. 91 (1): 12–21. doi:10.1016/j.ygeno.2007.10.009. PMC 2267438. PMID 18060738.
Lloyd Webber began setting Eliot's poems to music in 1977 and the compositions were first presented as a song cycle in 1980. Producer Cameron Mackintosh then recruited director Trevor Nunn and choreographer Gillian Lynne to turn the songs into a complete musical. Cats opened to positive reviews at the New London Theatre in the West End in 1981 and then to mixed reviews at the Winter Garden Theatre on Broadway in 1982. It won numerous awards including Best Musical at both the Laurence Olivier and Tony Awards. Despite its unusual premise which deterred investors initially, the musical turned out to be an unprecedented commercial success, with a worldwide gross of $3.5 billion by 2012.
^ Jump up to: a b Driscoll, C. A.; Macdonald, D. W.; O'Brien, S. J. (2009). "In the Light of Evolution III: Two Centuries of Darwin Sackler Colloquium: From Wild Animals to Domestic Pets – An Evolutionary View of Domestication". Proceedings of the National Academy of Sciences of the United States of America. 106 (S1): 9971–9978. Bibcode:2009PNAS..106.9971D. doi:10.1073/pnas.0901586106. PMC 2702791. PMID 19528637.
We are supported by the entire team at Atlas Games, including, especially, Michelle Nephew, the co-owner of the company who, along with her wonderful children, discovered the joys of Magical Kitties at Con of the North all those years ago. Our grateful thanks, too, for all of the friends, fans, and playtesters who’ve also done so much to make this edition of Magical Kitties Save the Day a reality.

Within the first 2 days after birth, kittens acquire passive immunity from their mother’s milk.[30] Milk within the first few days of parturition is called colostrum, and contains high concentrations of immunoglobulins.[30] These include immunoglobulin A and immunoglobulin G which cross the intestinal barrier of the neonate.[29] The immunoglobulins and growth factors found in the colostrum begin to establish and strengthen the weak immune system of the offspring.[31] Kittens are able to chew solid food around 5–6 weeks after birth, and it is recommended that 30% of their diet should consist of solid food at this time.[32] The kitten remains on the mother’s milk until around eight weeks of age when weaning is complete and a diet of solid food is the primary food source.[23]
English-language touring companies have also toured the European region extensively. International tours in the early to late 2000s included stops in Sweden, Norway,[219] Finland,[220] Greece,[188] Portugal,[221] Germany,[222] and Italy.[223] The 2013–2014 UK tour visited cities in Belgium,[214][224] Greece, Italy,[225] Monaco, and Portugal.[153] Most recently, a UK production played in numerous European cities from 2016 to 2019, with tour stops in Switzerland, Croatia, Belgium, Poland, Bulgaria, Germany, Norway, Sweden, Finland, Denmark, Netherlands, and Luxembourg.[226] These European tours have featured several notable performers in the role of Grizabella, including Pernilla Wahlgren (Sweden; 2003),[227] Katarína Hasprová (Slovakia; 2016)[228] and Jenna Lee-James (Netherlands; 2018–2019).[229]
Although wildcats are solitary, the social behavior of domestic cats is much more variable and ranges from widely dispersed individuals to feral cat colonies that gather around a food source, based on groups of co-operating females.[130][131] Within such groups, one cat is usually dominant over the others.[132] Each cat in a colony holds a distinct territory, with sexually active males having the largest territories, which are about 10 times larger than those of female cats and may overlap with several females' territories.[87] These territories are marked by urine spraying, by rubbing objects at head height with secretions from facial glands, and by defecation.[87] Between these territories are neutral areas where cats watch and greet one another without territorial conflicts. Outside these neutral areas, territory holders usually chase away stranger cats, at first by staring, hissing, and growling and, if that does not work, by short but noisy and violent attacks. Despite some cats cohabiting in colonies, they do not have a social survival strategy, or a pack mentality and always hunt alone.[133]
Nunn was also adamant that the orchestra for Cats be hidden backstage — out of the audience's view — so as not to break the immersion.[90] Adding to the experience, the show usually includes a lot of audience interaction, such as during the overture when the cast don flashing "green eyes" as they make their way through the audience in the darkened theatre.[80][91] In the original Broadway production, catwalks were built to connect the stage to the boxes and balcony so as to give the cast access to the entire auditorium during the show.[92]
One of the first things you should do with your new cat, if not the very first, is take him in for an exam. This trip is almost as important for the owner as it is the kitten, because it not only tests for health issues like birth defects, parasites, and feline leukemia, but it allows you to ask those all important questions including advice on litterbox training your kitten.
In isolated landmasses, such as Australasia, there are often no other native, medium-sized quadrupedal predators (including other feline species); this tends to exacerbate the impact of feral cats on small native animals.[214] Native species such as the New Zealand kakapo and the Australian bettong, for example, tend to be more ecologically vulnerable and behaviorally "naive", when faced with predation by cats.[215] Feral cats have had a major impact on these native species and have played a leading role in the endangerment and extinction of many animals.[216]
The gestation period of queens is between 64 and 67 days, with an average of 66 days.[183] Data on reproductive capacity of more than 2,300 free-ranging queens were collected during a study between May 1998 and October 2000. They had one to six kittens per litter, with an average of three kittens. They produced a mean of 1.4 litters per year, but a maximum of three litters in a year. Of 169 kittens, 127 died before they were six months old due to a trauma caused in most cases by dog attacks and road accidents.[9] The first litter is usually smaller than subsequent litters. Kittens are weaned between six and seven weeks of age. Queens normally reach sexual maturity at 5–10 months, and males at 5–7 months. This varies depending on breed.[178]
If you’re a roleplayer with years of experience, Magical Kitties makes it easy to introduce your friends and family your favorite hobby. But if you’ve never played a roleplaying game before, Magical Kitties Save the Day makes it easy to try something new! Between The Big Adventure, “The Game Master’s First Adventure,” and the Kitty Tips! you’ll find throughout every book, it’ll be like we’re right there by your side the whole time.
Vitamin A is required in kitten diets because cats cannot convert carotenes to retinol in the intestinal mucosa because they lack the enzyme so this vitamin must be supplement in the diet.[24][42] Vitamin E is another required vitamin in kitten diets seeing as deficiency leads to steatitis, causing the depot fat to become firm and yellow-orange in colour, which is painful and leads to death.[42] Also, vitamin D is an essential vitamin because cats cannot convert it from precursors in the skin.[24]
Cats have excellent hearing and can detect an extremely broad range of frequencies. They can hear higher-pitched sounds than either dogs or humans, detecting frequencies from 55 Hz to 79,000 Hz, a range of 10.5 octaves, while humans and dogs both have ranges of about 9 octaves.[80][81] Cats can hear ultrasound, which is important in hunting[82] because many species of rodents make ultrasonic calls.[83] However, they do not communicate using ultrasound like rodents do. Cats' hearing is also sensitive and among the best of any mammal,[80] being most acute in the range of 500 Hz to 32 kHz.[84] This sensitivity is further enhanced by the cat's large movable outer ears (their pinnae), which both amplify sounds and help detect the direction of a noise.[82]